Volume 15, Number 2, June 2003

Histological Evaluation of an 11-year-old Hydroxyapatite Ceramic Implant in Mandibular Bone

Kenji Kurashina,1 Toshikazu Minemura,2 Hiroshi Kurita,1 Qiang Wu1

1Department of Dentistry and Oral Surgery, Shinshu University School of Medicine, Matsumoto, Japan
2Department of Dentistry and Oral Surgery, Iida Municipal Hospital, Iida, Japan

Abstract
There are no detailed long-term histological studies of hydroxyapatite implanted in human bone tissue. This report is of histological and radiographic examination of a patient with mandibular bone implanted with hydroxyapatite ceramics after cyst ennucleation and a good clinical course for 10 years. The mandibular bone was resected 11 years after the initial operation because of infection. Histology of the retrieved mandibular bone revealed that bone tissue proliferated into interparticular spaces and attached to the hydroxyapatite ceramics surfaces in the non-infected portion and that hydroxyapatite ceramics disappeared with bone destruction in the infected portion. From the histological results, clinical findings, and chronological radiographic findings for 10 years, it was concluded that hydroxyapatite ceramics could maintain their favourable properties as a bone substitute in human bone for a long time.

Key words:
Hydroxyapatite, Mandible

Asian J Oral Maxillofac Surg. 2003;15:142-145.
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