Volume 15, Number 2, June 2003

Survival Rates After Surgical or Non-surgical Treatment for Advanced Resectable Squamous Cell Carcinoma of the Oral Cavity and Oropharynx

Hiroshi Kurita,1 Hiroichi Kobayashi,1 Takeshi Koike,1 Shigeru Fujimori,1 Kenji Kurashina,1 Naoto Shikama2

1Department of Dentistry and Oral Surgery, and 2Department of Radiology, Shinshu University School of Medicine, Matsumoto, Japan

Objective: To determine the difference in survival rates between surgical and non-surgical treatment for resectable squamous cell carcinoma of the oral cavity and oropharynx.
Patients and Methods: A retrospective chart review of 53 patients in a single institution who preferred surgical treatment and 11 patients who preferred non-surgical treatment.
Results: The overall survival probability rate of the surgically-treated patients was 90% at 1 year, 76% at 2 years, and 61% at 5 years, while that of the non-surgically-treated patients was 60%, 30%, and 15%, respectively. The difference in the cause-specific survival rate between the 2 groups was significant (log-rank test, p < 0.05). There were significant differences in the distribution of patient's age, T-stage, N-stage, and performance status. However, the Cox multivariate analysis revealed that the treatment was a significant independent predictor.
Conclusion: The results suggest that when non-surgical treatment is given for resectable cancer, the probability of survival from the disease is 30% and death would occur within 2 years. The survival rate is half that of those who undergo radical surgery (67%).

Key words: Oral cancer, Surgery, Survival

Asian J Oral Maxillofac Surg. 2003;15:96-100.
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