Volume 15, Number 3, September 2003

Solitary Fibrous Tumour of the Buccal Mucosa: Immunohistochemical and Ultrastructural Observation

Souichi Yanamoto,1 Goro Kawasaki,1 Akio Mizuno,1 Shuichi Fujita2

1Division of Oral and Maxillofacial Surgery and 2Division of Oral Pathology and Bone Metabolism, Department of Developmental and Reconstructive Medicine, Course of Medical and Dental Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

Solitary fibrous tumour is a benign soft tissue tumour, most often localised in the pleura but recently described in other body sites. However, solitary fibrous tumour in the oral cavity is distinctly uncommon. A patient with this tumour in the oral cavity is described in this report. Magnetic resonance angiography revealed that the tumour was suspected to be a haemangioma. The tumour was surgically removed and was found to 3.5 x 2.8 x 2.5 cm in size. Histologically, the tumour was comprised of numerous ovoid- or spindle-shaped cells and many blood vessels with haemangiopericytoma-like appearance. The tumour cells immunoreacted for vimentin, CD34, and bcl-2. Ultrastructurally, a small amount of collagen fibrils were associated with the neoplastic cells, and cytoplasmic organelles were not developed. The tumour was considered to be predominantly composed of immature fibroblasts. The patient has had no recurrence.

Key words:
Buccal mucosa, Immunohistochemistry, Tumor, Ultrastructure

Asian J Oral Maxillofac Surg. 2003;15:199-204.
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