Volume 16, Number 1, March 2004
| | Salivary Duct Carcinoma of the Minor Salivary Glands |
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Akiyuki Maeda, Tsunehisa Shimoda, Satoru Ozeki, Takeshi Honda
Department of Oral and Maxillofacial Surgery, Fukuoka Dental College, Fukuoka, Japan
Abstract
Salivary duct carcinoma is characterised by aggressive behaviour, with a high risk of local recurrence, and regional and distant metastasis. This report describes a patient with salivary duct carcinoma that originated in the minor salivary glands of the mucosa over the maxilla. Microscopically, vascular invasion varied from 4 to 5 per 10 high-power fields, and immunohistochemical staining with E26 transformation specific-1 was demonstrated in the tumour cells. Ki67 positivity was also revealed in 52% of the specimens examined. These results suggest that salivary duct carcinoma is a highly aggressive malignant salivary gland tumour due to proliferative cell activity, angiogenesis, and vascular invasion.
Key words: Ki67, Minor salivary gland, Salivary duct carcinoma, Vascular invasion
Asian J Oral Maxillofac Surg. 2004;16:51-55.
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