Volume 16, Number 2, June 2004

Risk Factors for Postoperative Local Recurrence of Tongue Carcinoma

Hideo Kurokawa,1 Min Zhang,2 Yoshihiro Yamashita,1 Shinobu Matsumoto,1 Hiroshi Takano,1 Katsuyuki Funaki,1 Taiki Tomoyose,1 Tomoaki Shibuya,1 Hiroshi Fukuyama,2 Tetsu Takahashi1

1Second Department of Oral and Maxillofacial Surgery, and 2Department of Oral Pathology, Kyushu Dental College, Kitakyushu, Japan

Objective: To identify the clinicopathologic factors associated with postoperative local recurrence in patients with carcinoma of the tongue.
Patients and Methods: Clinicopathologic factors were reviewed in 50 patients seen between 1985 and 1996 with previously untreated stage I or stage II squamous cell carcinoma of the tongue. All of the patients underwent partial glossectomy without elective neck dissection. Postoperative local recurrence occurred in 13 patients (26.0%) within 8 to 16 months of surgery for the primary tumour. Clinicopathologic factors were analysed using logistic regression to determine factors predicting postoperative local recurrence of tongue carcinoma.
Results: Postoperative local recurrence was positively associated with tumour size (≥30 mm), tumour thickness (≥4 mm), and epithelial dysplasia score within 3 mm of the surgical margin (≥4 points). In a multivariate logistic regression analysis, patients with epithelial dysplasia score of ≥4 points within 3 mm of the surgical margin had a predictive value for postoperative local recurrence (odds ratio, 36.6; p < 0.0001).
Conclusions: Patients with an epithelial dysplasia score of ≥4 points within 3 mm of the surgical margin have a higher risk of postoperative local recurrence. It is recommended that this diagnostic factor be used in deciding about re-excision or additional therapy.

Key words:
Epithelial dysplasia, Neoplasm recurrences, local, Risk factor, Tongue cancer

Asian J Oral Maxillofac Surg. 2004;16:91-96.
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