Volume 17, Number 4, December 2005
| | Adenomatoid Odontogenic Tumour of the Maxilla: Immunohistochemical Study |
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Hiroyuki Suzuki, Kenji Hashimoto
Department of Oral and Maxillofacial Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan
Abstract
To define the nature of the tumour cells in adenomatoid odontogenic tumour and assess whether the tumour is a neoplastic or developmental lesion, the expression of 2 markers of the cell cycle, p16INK4A and Ki-67, and the alteration of 1 gene, the p16INK4A gene, were evaluated in a patient with adenomatoid odontogenic tumour. The results showed that neither p16INK4A expression nor Ki-67 expression were detected. Based on the immunohistochemical and fluorescence in situ hybridisation results, adenomatoid odontogenic tumour is not considered to be a neoplastic growth of the odontogenic epithelium.
Key words: Adenomatoid tumor, Immunohistochemistry, Odontogenic tumors
Asian J Oral Maxillofac Surg. 2005;17:267-271.
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