Volume 18, Number 1, March 2006

Fibrous Dysplasia-like Jaw Enlargement following Treatment with Growth Hormone


Akio Kano, Kenji Mogi, Akihide Negishi, Kuninori Sasaoka, Keiji Kanno, Yoshiki Nakasone, Kouichi Ishihara
Department of Stomatology and Maxillofacial Surgery, Subdivision of Oncology, Division of Biosystem Medicine, School of Medicine, Gunma University Graduate School, Gunma-ken, Japan

Abstract
This report is of a 10-year-old boy with unusual fibrous dysplasia-like lesions in the jaw. The patient had been taking recombinant human growth hormone for the treatment of short stature due to growth hormone deficiency from the age of 8 to 10 years. The lesions were exceptionally large and affected the entire maxilla and mandible. An association with growth hormone therapy was suspected.

Key words: Dwarfism, pituitary, Facial bones, Fibrous dysplasia of bone, Human growth hormone, Jaw

Asian J Oral Maxillofac Surg. 2006;18:62-66.

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