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Volume 19, Number 4, December 2007

Squamous Cell Carcinoma of the Lower Lip in an Elderly Patient with Xeroderma Pigmentosum


Kenichi Hiramoto, Kasumi Shimizu, Motoshi Narita, Tohru Tokuda, Taku Murata, Toshiro Tagawa
Department of Oral and Maxillofacial Surgery, Division of Reparative and Regenerative Medicine, Institute of Medical Science, Mie University Graduate School of Medicine, Mie, Japan

Abstract 
Xeroderma pigmentosum is a rare, autosomal recessive genetic disease accompanied by abnormal DNA function due to damage by ultraviolet radiation. Xeroderma pigmentosum typically has general features of high light sensitivity and a high incidence of skin cancer in regions exposed to sunlight. We report the case of squamous cell carcinoma of the lower lip in an 82-year-old patient with xeroderma pigmentosum who was successfully treated with peplomycin after first receiving treatment for diabetes.

Key words: ExostoAged, 80 and over, Carcinoma, squamous cell, Lip, Peplomycin, Xeroderma pigmentosum

Asian J Oral Maxillofac Surg. 2007;19:222-225.

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