Volume 20, Number 3, September 2008
| | Mesenchymal Chondrosarcoma of the Mandible |
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Yoshiyuki Uchiyama,1 Tetsuji Nagata,1 Hiroyuki Suzuki,1 Akiyoshi Gotoh,2 Fumihiko Matsushita,3 Satoshi Baba,4 Kenji Hashimoto1
1Department of Dentistry and Oral and Maxillofacial Surgery, Hamamatsu University School of Medicine, Shizuoka, 2Department of Dentistry and Oral and Maxillofacial Surgery, Nara Hospital, Kinki University School of Medicine, Nara, 3Department of Oral and Maxillofacial Surgery, Haibara General Hospital, Shizuoka, and 4Department of Pathology, Hamamatsu University School of Medicine, Shizuoka, Japan
Abstract
This report describes a 33-year-old man diagnosed with mesenchymal chondrosarcoma. The patient was referred with a painless, elastic hard mass in the retromolar region. Radiologically, the tumour presented as an expansion of the right mandibular ramus partly extending to the inferior masseter. A segmental mandibulectomy was performed during the initial surgery. Histopathologically, the tumour showed well-differentiated hyaline cartilage tissue in the lobules with cartilaginous islands and small cells. Immunohistochemically, the tumour cells reacted positively to clusters of differentiation99 and S-100 protein. The tumour recurred in the right inferior temporal fossa 3 years after the initial surgery. Although radical right maxillectomy and dissection of the inferior temporal fossa were carried out immediately, the patient developed multiple pulmonary metastases after 10 months.
Key words: Chondrosarcoma, mesenchymal, Mandibular neoplasms, Neoplasm metastasis
Asian J Oral Maxillofac Surg. 2008;20:144-147.
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