Volume 20, Number 3, September 2008
| | Malignant Pheochromocytoma with Mandibular Metastasis |
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Gosei Ueda,1,2 Hajime Sunakawa,2 Akira Arasaki,2 Keiichi Arakaki,2 Toshiyuki Nakasone,2 Tsutomu Higa2
1Department of Oral and Maxillofacial Surgery, Okinawa Prefectural Miyako Hospital, and 2Department of Oral and Maxillofacial Functional Rehabilitation, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan
Abstract
Malignant pheochromocytoma of the mandible is an extremely uncommon tumour. This report describes a 59-year-old woman with pheochromocytoma metastatic to the mandible. The patient was referred with a painless mandibular swelling on the right side. She had undergone dual tumour ablation for a pheochromocytoma of the adrenal medulla 7 years and 6 months previously, and for a pheochromocytoma metastatic lesion on the pelvis 2 years and 8 months previously. Radiographic examinations revealed a well-circumscribed radiolucent lesion of the mandibular ramus. A definitive diagnosis of malignant pheochromocytoma was made following a partial mandibulectomy. The patient died of disseminated intravascular coagulation and multiple bone metastases of pheochromocytoma about 10 years after the initial diagnosis of disease.
Key words: Mandible, Neoplasm metastasis, Pheochromocytoma
Asian J Oral Maxillofac Surg. 2008;20:167-170.
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